Very few people work alone. It's vital that you know how to get along with your co-workers by sharing the work space in a respectful, mindful and responsible way.
CONSIDER YOUR SET-UP
What could you do to feel more comfortable? Do you need to face opposite the flow of traffic to minimise visual distraction? Or does having you computer open to passers-by make you feel comprised? Consider using furniture in a way that can create boundaries.
Remember to take breaks to reset. Try stretching every so often, or perhaps a walking meeting. It's also a good idea to take your lunch break away from the office/workspace.
UTILISE OTHER SPACES
Find out about breakaway spaces, conference rooms and use these when you need to have longer conversations or need a quiet space to concentrate. This is particularly important when you work in an open or shared space.
Talk to your colleagues about ways to make the space work for everybody. It's important to try this before escalating matters to your supervisor.